Search results for " Early Detection"
showing 10 items of 19 documents
Early miR-223 Upregulation in Gastroesophageal Carcinogenesis
2017
Objectives: To test miR-223 upregulation during gastric (intestinal-type) and Barrett esophageal carcinogenesis. Methods: miR-223 expression was assessed by quantitative reverse transcription polymerase chain reaction in a series of 280 gastroesophageal biopsy samples representative of the whole spectrum of phenotypic changes involved in both carcinogenetic cascades. The results were further validated by in situ hybridization on multiple tissue specimens obtained from six surgically treated gastroesophageal adenocarcinomas. miR-223 expression was also assessed in plasma samples from 30 patients with early stage (ie, stages I and II) gastroesophageal adenocarcinoma and relative controls. Res…
Proposal of a Citrus translational genomic approach for early and infield detection of Flavescence dorée in Vitis
2014
Flavescence dore´e (FD) is one of the most widely known grapevine yellows disease and one of the most unabated worldwide in the viticulture sector. In this paper, we outline a strategy for developing an integrated system of technologies to enable rapid, early disease FD detection and diagnosis. We propose the deployment of a newly developed sensor device, the differential mobility spectrometer (DMS), which has shown positive results with a similar vector-borne disease in Citrus. We have previously demonstrated that the gas chromatograph DMS (GC/DMS) can distinguish various citrus diseases, and the system may also allow detection of volatile organic compound (VOC) signals from a tree of othe…
Detection of Parietaria Mottle Virus by RT-qPCR: An Emerging Virus Native of Mediterranean Area That Undermine Tomato and Pepper Production in Southe…
2021
Parietaria mottle virus (PMoV) is considered an emerging virus in many countries of the Mediterranean basin, especially on tomato and pepper crops. Symptoms on tomato leaves and fruits can be easily confused with those induced by cucumber mosaic virus (CMV) with necrogenic satellite RNA (CMV-satRNA), tomato spotted wilt virus (TSWV) or tomato mosaic virus (ToMV). Mixed infection of these viruses has been also reported in some tomato cultivars, with an increase in the complexity of the symptoms and severity of the disease. Although a specific serum and riboprobes have been produced, nowadays no sensitive diagnostic methods are available for the rapid PMoV detection. Here, we have developed a…
Screening of colorectal cancer: present and future
2017
Colorectal cancer (CRC) is the third most common cancer in males and second in females, and the fourth most common cause of cancer death worldwide. Currently, about 60-70% of diagnosed cases in symptomatic patients are detected at an advanced stage of disease. Earlier stage detection through the use of screening strategies would allow for better outcomes in terms of reducing the disease burden. Areas covered: The aim of this paper is to review the current published evidence from literature which assesses the performance and effectiveness of different screening tests for the early detection of CRC. Expert commentary: Adequate screening strategies can reduce CRC incidence and mortality. In th…
An API for Advanced Traffic Control in Diffserv Routers
2003
Distributed per-flow admission control is a promising solution for Differentiated Services networks. Its deployment in DiffSery domains requires the ability to suitably configure, in each network router, low-level packet forwarding mechanisms, such as packet dropping algorithms driven by traffic measurements. In this paper we first show that performance effectiveness is achieved by means of non traditional configuration of the forwarding mechanisms. Hence, we propose a modular Application Program Interface that allows to flexibly and adaptively configure the forwarding/dropping behavior associated to a router’s output queue, well beyond the traditional RED/RIO active queue management scheme…
First record of Heptapleurum arboricola Hayata (Araliaceae) as a casual non-native woody plant in the Mediterranean area
2021
I report here the first record of Heptapleurum arboricola Hayata (syn. Schefflera arboricola (Hayata) Merr.) (Araliaceae) as a casual non-native plant throughout the Mediterranean area. I observed the natural regeneration in urban areas at Castellammare del Golfo, a small coastal town in north-west Sicily (Mediterranean Italy). Due to the lack of self-sustaining populations and the short-term observational period, Heptapleurum arboricola should be considered as a casual species according to the classification of non-native plants. The detection of early signs of naturalization of non-native plants is of crucial importance for the management and control of invasive species. The main abiotic …
Semi-automated non-invasive diagnostics method for melanoma differentiation from nevi and pigmented basal cell carcinomas
2017
The incidence of skin cancer is still increasing mostly in in industrialized countries with light- skinned people. Late tumour detection is the main reason of the high mortality associated with skin cancer. The accessibility of early diagnostics of skin cancer in Latvia is limited by several factors, such as high cost of dermatology services, long queues on state funded oncologist examinations, as well as inaccessibility of oncologists in the countryside regions - this is an actual clinical problem. The new strategies and guidelines for skin cancer early detection and post-surgical follow-up intend to realize the full body examination (FBE) by primary care physicians (general practitioners,…
Usefulness of Stress Echocardiography in the Management of Patients Treated with Anticancer Drugs.
2021
In recent years, the survival of patients with cancer has improved thanks to advances in antineoplastic therapeutic protocols. This has led to an increasing burden of cardiovascular complications related to cancer treatment. Therefore, a new branch of cardiology has been created, ``cardio-oncology,'' with the aims of preventing cardiovascular complications related to antineoplastic treatment, achieving early diagnosis and treatment of any complications, and allowing completion of the expected antineoplastic treatment. Stress echocardiography has a pivotal role in achieving a timely diagnosis of coronary artery disease and thus is the best management approach in this clinical setting. Athero…
A genetic algorithm for the design of a fuzzy controller for active queue management
2003
Active queue management (AQM) policies are those\ud policies of router queue management that allow for the detection of network congestion, the notification of such occurrences to the\ud hosts on the network borders, and the adoption of a suitable control\ud policy. This paper proposes the adoption of a fuzzy proportional\ud integral (FPI) controller as an active queue manager for Internet\ud routers. The analytical design of the proposed FPI controller is\ud carried out in analogy with a proportional integral (PI) controller,\ud which recently has been proposed for AQM. A genetic algorithm is\ud proposed for tuning of the FPI controller parameters with respect\ud to optimal disturbance rej…
Random Early Detection for Congestion Avoidance in Wired Networks: A Discretized Pursuit Learning-Automata-Like Solution
2010
Published version of an article in the journal: IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works In this paper, we present a learning-automata-like (LAL) mechanism for congestion avoidance in wired networks. Our algorithm, named as LAL random early detection (LALRED), is founded on the principles of the operations of existing RED con…